Qatar Biomedical Research Institute

Active

EX-QNRF-ARG-10: Novel Diagnostic Applications for Disease-Associated aggregates of Parkinson's disease and Related Disorders

El-Agnaf, O. M. A. (Lead Principal Investigator), Poovarangil Sudhakaran, I. (Post Doctoral Fellow), Mollenhauer, B. (Principal Investigator), Adeli, G. R. M. A. (Principal Investigator) & Emara, M. (Principal Investigator)

1/04/24 → 1/04/27

Project: Experimental Development/Translation Research

EX-QNRF-ARG-49: Characterization of all SARS-CoV-2 Mpro & PLpro protease cleavage sites and variants for identifying lead dual protease inhibitor compounds using novel dual color, BRET-based biosensors

Kolatkar, P. R. (Principal Investigator), Aouida, M. (Principal Investigator), Islam, Z. (Post Doctoral Fellow), Biswas, K. H. (Lead Principal Investigator), Geethakumari, A. M. (Post Doctoral Fellow), Khatib, H. A. (Principal Investigator) & Sultana, A. (Research Assistant)

1/04/24 → 1/04/27

Project: Basic Research

EX-QNRF-ARG-34: Functional characterization and pharmacological targeting of calcium signaling pathways for the treatment of autism spectrum disorders

Al Haj Zen, A. (Principal Investigator), Park, Y. (Lead Principal Investigator), Da'as, S. (Principal Investigator) & Ali Bakht Jamal, G. (Post Doctoral Fellow)

1/04/24 → 1/04/27

Project: Experimental Development/Translation Research

EX-QNRF-ARG-62: Investigation of the mechanisms underlying the protective effect of Glucagon-Like Peptide-1 Receptor agonists on Non-alcoholic Fatty Liver Disease in mice

Arredouani, A. (Lead Principal Investigator), AL Akl, N. (Research Associate), Khalifa, O. (Post Doctoral Fellow), Moustaid-Moussa, N. (Co-Lead Principal Investigator) & unamed (Research Assistant)

1/04/24 → 1/04/27

Project: Experimental Development/Translation Research

EX-QNRF-ARG-54: Towards better cancer care in pediatric oncology: exploring the biomarker and therapeutic potential of cancer testis antigens.

Decock, J. V. C. M. (Lead Principal Investigator), De la Fuente van Bentem, A. (Post Doctoral Fellow), Ozer, E. (Principal Investigator), Hendrickx, W. (Principal Investigator) & Ashraf, J. V. (Post Doctoral Fellow)

1/04/24 → 1/04/27

Project: Experimental Development/Translation Research

EX-Silverstein -1: Therapeutic Nanobody Development for Targeting α-Synuclein Aggregation in Parkinson's Disease, with Focus on Parkinson's Disease with GBA Mutation

El-Agnaf, O. M. A. (Lead Principal Investigator) & Mahmoud Mesleh, A. G. (Post Doctoral Fellow)

1/01/24 → 1/01/26

Project: Experimental Development/Translation Research

QBRI-CORE-000011: Development of ?-synuclein-Specific Nanobodies for Targeting Aggregation in Parkinson's Disease

El-Agnaf, O. M. A. (Lead Principal Investigator) & Bezard, D. E. (Principal Investigator)

1/01/24 → 31/12/26

Project: Experimental Development/Translation Research

QBRI-CORE-000012: Unlocking precision medicine in breast cancer: Generation of a Breast cancer Cancer Testis antigen Atlas (BCTa) for biomarker discovery and therapeutic target identification.

Decock, J. V. C. M. (Lead Principal Investigator)

1/01/24 → 31/12/26

Project: Experimental Development/Translation Research

QBRI-CORE-000013: Sox transcription factors: balancing pancreatic development and dysfunction in cancer

Kolatkar, P. R. (Lead Principal Investigator)

1/01/24 → 31/12/26

Project: Experimental Development/Translation Research

HBKU-OVPR-TG-Cycle-2-20: CRISPR-Cas9 functional screen to identify novel prognostics and therapeutics lncRNA targets in triple negative breast cancer

Shaath, H. (Research Associate), Albagha, O. (Principal Investigator), Alajez, N. (Lead Principal Investigator), Alam, T. (Principal Investigator) & Radhakrishnan, V. B. (Post Doctoral Fellow)

1/06/23 → 30/11/25

Project: Applied Research

HBKU-OVPR-TG-Cycle-2-10: A precision medicine approach to investigate autism-related functions of altered blood proteins as potential targets for autism therapy

Al-Shammari, A. R. M. A. (Lead Principal Investigator), Ltaief, S. (Research Associate), Farhan, M. (Principal Investigator) & Salim, S. S. U. K. (Post Doctoral Fellow)

1/06/23 → 31/05/25

Project: Applied Research

HBKU-OVPR-TG-Cycle-2-60: Dissecting the role of uncontrolled neural stem cell division in cortical neurogenesis and glioma genesis

Alkailani, M. I. G. (Research Associate), Al-Khadairi, G. M. (Research Associate), Aittaleb, M. (Principal Investigator), Tissir, F. (Lead Principal Investigator), Mahdi, A. (Graduate Student) & Al-Shammari, A. R. M. A. (Principal Investigator)

1/06/23 → 31/05/25

Project: Basic Research

HBKU-OVPR-TG-Cycle-2-38: Engineering a high affinity peptide combining computational and experimental methods towards precision medicine applications

Kolatkar, P. R. (Principal Investigator), Horn, H. F. (Principal Investigator), Islam, Z. (Post Doctoral Fellow), Biswas, K. H. (Lead Principal Investigator), Geethakumari, A. M. (Post Doctoral Fellow), Kafour, N. (Graduate Student), Fatima, A. (Graduate Student) & Uddin, S. M. N. (Graduate Student)

1/06/23 → 31/05/25

Project: Applied Research

HBKU-OVPR-TG-Cycle-2-61: Drug screening for autism spectrum disorder using human induced pluripotent stem cells (iPSCs)

Ali Moussa, H. Y. (Research Associate), Al Haj Zen, A. (Principal Investigator), Park, Y. (Lead Principal Investigator) & Shin, K. C. (Post Doctoral Fellow)

1/06/23 → 30/09/25

Project: Applied Research

QBRI-CORE-000005: From Molecular Profiling to Diagnostics and Drug Targets: Integration for Precision Medicine in Breast Cancer

Al Ejeh, F. H. S. (Lead Principal Investigator) & Afifi, D. N. (Principal Investigator)

1/01/23 → 31/12/25

Project: Experimental Development/Translation Research

QCRI-CORE-000017: Non-BRCA breast cancer in the Middle East

Saad, M. (Lead Principal Investigator) & Alajez, N. (Technical Advisor)

1/01/23 → 31/12/25

Project: Basic Research

QBRI-CORE-000008: Identifying cellular sources of altered cytokines in autism

Al-Shammari, A. R. M. A. (Lead Principal Investigator)

1/01/23 → 31/12/25

Project: Experimental Development/Translation Research

QBRI-CORE-000009: Dissecting molecular pathways associated with autism using stem cell-based models and genomics approaches

Stanton, L. W. (Lead Principal Investigator)

1/01/23 → 31/12/25

Project: Experimental Development/Translation Research

QBRI-CORE-000004: Pathophysiological mechanisms of autism spectrum disorder (ASD) and neurodegenerative disease: development of biomarkers and therapeutics

Park, Y. (Lead Principal Investigator) & Da’as, D. S. (Principal Investigator)

1/01/23 → 31/12/25

Project: Experimental Development/Translation Research

QBRI-CORE-000006: The validation of a unique gene signature for triple negative breast cancer (TNBC) prognosis and predicting benefit for immunotherapy

Al-Muftah, M. A. Y. M. (Lead Principal Investigator) & Dermime, D. S. (Principal Investigator)

1/01/23 → 31/12/25

Project: Experimental Development/Translation Research

QBRI-CORE-000007: Identification of novel prognostic and therapeutic targets for breast cancer

Alajez, N. (Lead Principal Investigator), Abdel-Razeq, D. H. (Principal Investigator), Al-Omari, D. A. (Principal Investigator) & Tbakhi, D. A. (Principal Investigator)

1/01/23 → 31/12/25

Project: Experimental Development/Translation Research

QBRI-CORE-000003: Diagnostic and Predictive Biomarkers in Breast Cancer

Alajez, N. (Lead Principal Investigator), Gehani, D. S. (Principal Investigator), Bujassoum, D. S. (Principal Investigator), Abdel-Razeq, D. H. (Principal Investigator), Al-Omari, D. A. (Principal Investigator) & Tbakhi, D. A. (Principal Investigator)

6/12/20 → 6/12/25

Project: Experimental Development/Translation Research

QBRI-CORE-000010: Identifying Potential Biomarkers for Autism Spectrum Disorder

Al, D. A. (Consultant)

1/08/18 → 31/12/25

Project: Experimental Development/Translation Research

Finished

EX-ARGUS-1: ARGUS-MDS-ASD: Digital phenotyping for social communication behavior

Al-Shaban, F. A. W. (Lead Principal Investigator)

15/05/22 → 30/11/24

Project: Basic Research

HBKU--TDF-03-1: Prognostic plasma protein signature for early stratification of severe from non-severe COVID-19

Al Ejeh, F. H. S. (Lead Principal Investigator)

29/03/22 → 3/04/23

Project: Applied Research

QBRI-CORE-000001: Role of Mitochondria in the maturation and functionality of human pluripotent stem cell-derived pancreatic beta cells

Al-Siddiqi, H. H. A. A. (Lead Principal Investigator)

1/01/22 → 31/12/24

Project: Experimental Development/Translation Research

QBRI-CORE-000002: Evaluation of the prevalence of metabolically healthy obesity and metabolically unhealthy normal-weight in Qatar, and investigation of the underlying mechanisms using an integrated multi-omics approach: a cross-sectional study in the QBB cohort

Arredouani, A. (Lead Principal Investigator)

1/01/22 → 31/12/24

Project: Experimental Development/Translation Research

EX-QNRF-ECRA-1: MAFA and MAFB gene expression profiling and role during directed differentiation of human pluripotent stem cells to insulin producing pancreatic beta cells

Al-Siddiqi, H. H. A. A. (Lead Principal Investigator) & Allouch, A. (Research Assistant)

1/09/21 → 10/03/25

Project: Basic Research

HBKU-OVPR-TG-01-4: Regulatory interactions of autism-associated neural enhancers implicate novel genes in autism etiology

Ali Bakht Jamal, G. (Post Doctoral Fellow) & Farhan, M. (Principal Investigator)

1/06/21 → 30/11/23

Project: Applied Research

HBKU-OVPR-TG-01-3: Validation of LDHC as a novel target for precision medicine in breast cancer

Decock, J. V. C. M. (Lead Principal Investigator), Khan, O. M. (Principal Investigator) & Kohil, A. (Graduate Student)

1/06/21 → 30/11/23

Project: Experimental Development/Translation Research

EX-QNRF-ECRA-2: Neuro-immune interactions in autism spectrum disorder

Al-Shammari, A. R. M. A. (Lead Principal Investigator)

1/02/21 → 1/02/24

Project: Experimental Development/Translation Research

EX-QNRF-MME-7: Biological conversion of fuel synthesis process water to single cell protein for aquaculture feed using purple phototrophic bacteria

Kolatkar, P. R. (Principal Investigator), Mckay, G. (Lead Principal Investigator), Wada, O. (Graduate Student), Alli, S. A. (Graduate Student), Abdelnabi, M. (Graduate Student), Student-4, G. (Graduate Student), Technician-1, L. (Lab Technician), Liu, D. H. (Principal Investigator), Zhang, P. X. (Principal Investigator) & Vincent, D. A. (Principal Investigator)

9/09/20 → 9/03/24

Project: Applied Research

EX-QNRF-NPRPS-53: Functional characterization of long non-coding RNA (lncRNA) and microRNA (miRNA) transcriptional landscape predictive of response to neoadjuvant chemotherapy in triple negative breast cancer

Alajez, N. (Lead Principal Investigator), Elango, R. (Post Doctoral Fellow), Technician-2, L. (Lab Technician) & Johnson, P. R. (Principal Investigator)

5/01/20 → 5/10/23

Project: Experimental Development/Translation Research

EX-QNRF-NPRPS-3: Corneal Confocal Microscopy: A rapid diagnostic and prognostic imaging biomarker for neurodegeneration in dementia

El-Agnaf, O. M. A. (Lead Principal Investigator) & Poovarangil Sudhakaran, I. (Research Associate)

5/01/20 → 5/01/24

Project: Experimental Development/Translation Research

EX-QNRF-NPRPS-54: Therapeutic potential of DNAJB3/HSP-40 as a novel biomarker for obesity-induced insulin resistance and diabetes

Kolatkar, P. R. (Lead Principal Investigator), Diane, A. (Principal Investigator), Assistant-1, R. (Research Assistant), Assistant-2, R. (Research Assistant), Assistant-3, R. (Research Assistant), Ashawesh, D. K. (Principal Investigator), Dukhan, D. K. M. (Principal Investigator), Elkum, D. N. (Principal Investigator) & Moustaid-Moussa, P. N. (Principal Investigator)

12/05/19 → 10/08/23

Project: Experimental Development/Translation Research

Qatar Biomedical Research Institute

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