Dr Ayman Al Haj Zen is an Associate Professor at the College of Health and Life Sciences at Hamad Bin Khalifa University. He obtained his PhD from the University of Paris VII, where he studied the role of small proteoglycans in regulating vascular repair and atherosclerosis. Afterward, he moved to England and worked as a Postdoctoral Researcher at various institutions, including the London Research Institute, the University of Bristol, and the University of Oxford. During this time, he focused on studying the role of cell-cell communication signaling in ischemia-induced angiogenesis and vascular regeneration.

In 2013, Dr. Al Haj Zen received an intermediate research fellowship from the British Heart Foundation (Oxford) Centre of Research Excellence allowing him to establish his independent research program in vascular biology and drug discovery at the University of Oxford. His research centered on identifying new therapeutic targets and strategies to modulate angiogenesis and vascular response in diseases such as ischemic vascular disease, atherosclerosis, vascular dementia, and cancer.

His lab develops 3D microfluidics organ-on-chip disease models combined with high throughput quantitative image-based approaches to conduct genetic and drug screens that have applications in understanding underlying disease mechanisms and developing new therapeutics and personalized medicines.

• Functional characterization of GWAS candidate genes of coronary artery disease
• Target and drug discovery using a high-throughput phenotypic screening platform
• Advanced human disease modeling using 3D microfluidics organ-on-chip and bioprinting technologies
• Understanding the mechanisms of angiogenesis and microvasculature instability in diseases such as atherosclerosis, peripheral artery disease, diabetes, and cancer metastasis