Projects per year
Personal profile
Biography
Dr. Decock received her Master of Science (MSc) in Biomedical Sciences from the Free University of Brussels (VUB, Belgium) and completed her Doctor of Philosophy (PhD) in Medical Sciences at the Catholic University of Leuven, KU Leuven, Belgium. Her doctoral research focused on the cancer degradome, the repertoire of proteases in the tumor microenvironment that contribute to shaping the extracellular environment and modulating pericellular signaling, thereby affecting tumor progression and clinical outcome. Prior to joining QBRI, she was a postdoctoral fellow at the University of East Anglia (UK) where she studied the role of several protease families in cancer.
Dr Decock’s research focuses on advancing our current understanding of breast cancer to help accelerate the breast cancer field and advance the development of new treatments. Her research efforts address two pivotal and emerging key areas in breast cancer research; tumor antigen discovery & therapeutics and tumor immunology. Currently, a main theme in her research activities is centered around the exploration of the potential of cancer testis antigens as prime therapeutic anti-cancer targets and modulators of anti-tumor immunity.
Education/Academic qualification
Medical Sciences, PhD, The clinical relevance of (circulating) proteases in breast cancer: matrix metalloproteinases and cathepsins., KU Leuven
2003 → 2008
Biomedical Sciences, Master, "Might heterozygous BRCA1- and BRCA2- mutation have an influence on the stability of the genomic DNA?, Vrije Universiteit Brussel
2000 → 2002
Keywords
- RC0254 Neoplasms. Tumors. Oncology (including Cancer)
- breast cancer
- cancer testis antigens
- tumor immunology
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Collaborations and top research areas from the last five years
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EX-QNRF-ARG-54: Towards better cancer care in pediatric oncology: exploring the biomarker and therapeutic potential of cancer testis antigens.
Decock, J. V. C. M. (Lead Principal Investigator), De la Fuente van Bentem, A. (Post Doctoral Fellow), Ozer, E. (Principal Investigator), Hendrickx, W. (Principal Investigator) & Ashraf, J. V. (Post Doctoral Fellow)
1/04/24 → 1/04/27
Project: Experimental Development/Translation Research
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QBRI-CORE-000012: Unlocking precision medicine in breast cancer: Generation of a Breast cancer Cancer Testis antigen Atlas (BCTa) for biomarker discovery and therapeutic target identification.
Decock, J. V. C. M. (Lead Principal Investigator)
1/01/24 → 31/12/26
Project: Experimental Development/Translation Research
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HBKU-OVPR-TG-01-3: Validation of LDHC as a novel target for precision medicine in breast cancer
Decock, J. V. C. M. (Lead Principal Investigator), Khan, O. M. (Principal Investigator) & Kohil, A. (Graduate Student)
1/06/21 → 30/11/23
Project: Experimental Development/Translation Research
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Targeting of lactate dehydrogenase C dysregulates the cell cycle and sensitizes breast cancer cells to DNA damage response targeted therapy
Naik, A. & Decock, J., Feb 2022, In: Molecular Oncology. 16, 4, p. 885-903 19 p.Research output: Contribution to journal › Article › peer-review
Open Access16 Citations (Scopus) -
Immunomodulatory effects of tumor Lactate Dehydrogenase C (LDHC) in breast cancer
Naik, A., Thomas, R., Al-Khalifa, A., Qasem, H. & Decock, J., Dec 2025, In: Cell Communication and Signaling. 23, 1, 145.Research output: Contribution to journal › Article › peer-review
Open Access -
In-house assays for detecting anti-SARS-CoV-2 antibodies in serum and urine: Correlation with COVID-19 severity from a cohort study in Qatar
Vaikath, N. N., Al-Nesf, M. A., Majbour, N., Abdesselem, H. B., Gupta, V., Bensmail, I., Abdi, I. Y., Elmagarmid, K. A., Shabani, S., Sudhakaran, I. P., Ghanem, S. S., Al-Maadheed, M., Mohamed-Ali, V., Blackburn, J. M., Decock, J. & El-Agnaf, O. M. A., Jun 2025, In: Journal of Infection and Public Health. 18, 6, 9 p., 102744.Research output: Contribution to journal › Article › peer-review
Open Access -
Longitudinal cellular and humoral immune responses following COVID-19 BNT162b2-mRNA-based booster vaccination of craft and manual workers in Qatar
Thomas, R., Zaqout, A., Meqbel, B., Jafar, U., Vaikath, N. N., Aldushain, A., Naik, A., Shaath, H., Al-Akl, N. S., Adam, A., Moussa, H. Y. A., Shin, K. C., Taha, R. Z., Abukhattab, M., Almaslamani, M. A., Alajez, N. M., Arredouani, A., Park, Y., Abdulla, S. A. & El-Agnaf, O. M. A. & 2 others, , 2025, In: Frontiers in Immunology. 16, 1557426.Research output: Contribution to journal › Article › peer-review
Open Access -
Cancer testis antigens: Emerging therapeutic targets leveraging genomic instability in cancer
Naik, A., Lattab, B., Qasem, H. & Decock, J., 21 Mar 2024, In: Molecular Therapy: Oncology. 32, 1, 200768.Research output: Contribution to journal › Review article › peer-review
Open Access1 Citation (Scopus)