Projects per year
Personal profile
Research Interests
My research interests center on understanding the molecular mechanisms behind brain diseases, particularly neurodevelopmental and psychiatric disorders such as Schizophrenia, Depression, Autism, and Cerebral Palsy. Leveraging human genetics, genomics, and OMICS technologies, we aim to identify key genes, proteins, and pathways associated with these conditions. Complementing this work, we employ computational modeling techniques to design targeted drugs that interact with disease-associated proteins. To validate our findings and assess drug efficacy, we utilize both Drosophila models and human neuronal cell lines in our research. Ultimately, our goal is to translate these discoveries into innovative treatments that can significantly impact patient care and outcomes in the field of brain diseases.
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Collaborations and top research areas from the last five years
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HBKU-OVPR-TG-Cycle-2-10: A precision medicine approach to investigate autism-related functions of altered blood proteins as potential targets for autism therapy
Al-Shammari, A. R. M. A. (Lead Principal Investigator), Ltaief, S. (Research Associate), Farhan, M. (Principal Investigator) & Salim, S. S. U. K. (Post Doctoral Fellow)
1/06/23 → 31/05/25
Project: Applied Research
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EX-QNRF-NPRPS-17: A Precision Medicine Initiative To Target Paediatric Cerebral Palsy, A Movement Disorder
Albagha, O. (Principal Investigator), Farhan, M. (Lead Principal Investigator), El Hajj, N. (Principal Investigator), Grimshaw, P. (Principal Investigator), Ahammad, F. (Graduate Student), Abu Snaimeh, H. (Graduate Student), Miranda, H. G. (Graduate Student), Assistant-2, R. (Research Assistant), Thornton, D. L. (Principal Investigator) & Collier, D. T. (Principal Investigator)
15/11/22 → 15/11/26
Project: Experimental Development/Translation Research
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EX-QNRF-NPRPS-23: A PRECISION MEDICINE APPROACH TO TARGET COLORECTAL CANCER
Farhan, M. (Principal Investigator), Khan, O. M. (Lead Principal Investigator), Keyan, K. (Graduate Student) & Kohil, A. (Graduate Student)
15/03/21 → 15/03/25
Project: Experimental Development/Translation Research
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HBKU-OVPR-TG-01-4: Regulatory interactions of autism-associated neural enhancers implicate novel genes in autism etiology
Ali Bakht Jamal, G. (Post Doctoral Fellow) & Farhan, M. (Principal Investigator)
1/06/21 → 30/11/23
Project: Applied Research
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Neuronal mechanisms regulating locomotion in adult Drosophila
Gowda, S. B. M., Banu, A., Hussain, S. & Mohammad, F., Apr 2024, In: Journal of Neuroscience Research. 102, 4, e25332.Research output: Contribution to journal › Review article › peer-review
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The ortholog of human ssDNA-binding protein SSBP3 influences neurodevelopment and autism-like behaviors in Drosophila melanogaster
Salim, S., Hussain, S., Banu, A., Gowda, S. B. M., Ahammad, F., Alwa, A., Pasha, M. & Mohammad, F., Jul 2023, In: PLoS Biology. 21, 7 July, e3002210.Research output: Contribution to journal › Article › peer-review
Open Access -
Gut microbiome and Parkinson's disease: Perspective on pathogenesis and treatment
Salim, S., Ahmad, F., Banu, A. & Mohammad, F., Aug 2023, In: Journal of Advanced Research. 50, p. 83-105 23 p.Research output: Contribution to journal › Article › peer-review
Open Access23 Citations (Scopus) -
Serotonin distinctly controls behavioral states in restrained and freely moving Drosophila
Gowda, S. B. M., Banu, A., Salim, S., Peker, K. A. & Mohammad, F., 20 Jan 2023, In: iScience. 26, 1, 20 p., 105886.Research output: Contribution to journal › Article › peer-review
Open Access5 Citations (Scopus) -
Serotonergic control of feeding microstructure in Drosophila
Banu, A., Gowda, S. B. M., Salim, S. & Mohammad, F., 17 Jan 2023, In: Frontiers in Behavioral Neuroscience. 16, 1105579.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus)