Synthesis And Evaluation of A Novel 2D Diphosphate Nanocrystalline Hydrogel With Antimicrobial and Biocompatible Properties

The project objectives include synthesizing and characterizing different compositions of 2D diphosphate nanocrystalline hydrogels, evaluating their biocompatibility and cytotoxicity using various in-vitro assays on neonatal fibroblasts and keratinocytes, and ex-ovo assays on chic embryos, and investigating their antimicrobial activity against common skin pathogens (Staphylococcus aureus, Escherichia coli, and Candida albicans). The significance of the project lies in the development of novel inorganic Mg diphosphate-based 2D hydrogels, which have the potential to revolutionize the treatment of skin infections and chronic wounds. Improved patient outcomes, reduced healthcare complications, and potential cost savings are among the anticipated impacts. QEERI/ECMP role is Conduct antimicrobial assays to evaluate the effectiveness of the synthesized hydrogel against pathogenic microorganisms. Methodology: Conduct antimicrobial assays on selected bacterial and fungal strain (s) to assess the inhibitory effect of the hydrogel. Deliverables: Compilation and analysis of antimicrobial assay results, including an assessment of the hydrogel's effectiveness against the tested pathogens.

Qatar University