2. Experience with nonmem: Analysis of serum concentration data in patients treated with mexiletine and lidocaine

S. Vozeh*, M. Wenk, F. Follath

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)

Abstract

The generality and flexibility of the computer package NONMEM also confront the user with the difficult task of choosing the model which best describes the data at hand. With two practical examples we show how one may proceed in building the population model for serum concentration measurements. Features of NONMEM are presented which help the user to make the choice among different models.

Original languageEnglish
Pages (from-to)305-315
Number of pages11
JournalDrug Metabolism Reviews
Volume15
Issue number1-2
DOIs
Publication statusPublished - 1984
Externally publishedYes

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