ALLD: Acute Lymphoblastic Leukemia Detector

Saleh Musleh, Mohammad Tariqul Islam, Mohammad Towfik Alam, Mowafa Househ, Zubair Shah, Tanvir Alam

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

5 Citations (Scopus)

Abstract

Acute Lymphoblastic Leukemia (ALL) is a life-threatening type of cancer wherein mortality rate is unquestionably high. Early detection of ALL can reduce both the rate of fatality as well as improve the diagnosis plan for patients. In this study, we developed the ALL Detector (ALLD), which is a deep learning-based network to distinguish ALL patients from healthy individuals based on blast cell microscopic images. We evaluated multiple DL-based models and the ResNet-based model performed the best with 98% accuracy in the classification task. We also compared the performance of ALLD against state-of-the-art tools utilized for the same purpose, and ALLD outperformed them all. We believe that ALLD will support pathologists to explicitly diagnose ALL in the early stages and reduce the burden on clinical practice overall.

Original languageEnglish
Title of host publicationInformatics and Technology in Clinical Care and Public Health
EditorsJohn Mantas, Arie Hasman, Mowafa S. Househ, Parisis Gallos, Emmanouil Zoulias, Joseph Liasko
PublisherIOS Press BV
Pages77-80
Number of pages4
ISBN (Electronic)9781643682501
DOIs
Publication statusPublished - 2022
Externally publishedYes

Publication series

NameStudies in Health Technology and Informatics
Volume289
ISSN (Print)0926-9630
ISSN (Electronic)1879-8365

Keywords

  • Acute lymphoblastic leukemia
  • Computer aided diagnosis (CAD)
  • Deep learning
  • Leukemia

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