TY - JOUR
T1 - Aluminum environmental pollution
T2 - the silent killer
AU - Alasfar, Reema H.
AU - Isaifan, Rima J.
N1 - Publisher Copyright:
© 2021, The Author(s).
PY - 2021/9
Y1 - 2021/9
N2 - The concern about aluminum (Al) toxicity has been proven in various cases. Some cases are associated with the fact that Al is a neurotoxic substance that has been found in high levels in the brain tissues of Alzheimer’s disease (AD), epilepsy, and autism patients. Other cases are related to infants, especially premature infants and ones with renal failure, who are at the risk of developing the central nervous system (CNS) and bone toxicity. This risk is a result of infants’ exposure to Al from milk formulas, intravenous-feeding solutions, and possibly from aluminum-containing vaccinations. Furthermore, most antiperspirants contain aluminum compounds that raise human exposure to toxic Al. This review paper is intended to discuss in detail the above concerns associated with aluminum, and hence urges the need for more studies exploring the effects of overexposure to Al and recommending mitigation actions.
AB - The concern about aluminum (Al) toxicity has been proven in various cases. Some cases are associated with the fact that Al is a neurotoxic substance that has been found in high levels in the brain tissues of Alzheimer’s disease (AD), epilepsy, and autism patients. Other cases are related to infants, especially premature infants and ones with renal failure, who are at the risk of developing the central nervous system (CNS) and bone toxicity. This risk is a result of infants’ exposure to Al from milk formulas, intravenous-feeding solutions, and possibly from aluminum-containing vaccinations. Furthermore, most antiperspirants contain aluminum compounds that raise human exposure to toxic Al. This review paper is intended to discuss in detail the above concerns associated with aluminum, and hence urges the need for more studies exploring the effects of overexposure to Al and recommending mitigation actions.
KW - Aluminum
KW - Alzheimer disease
KW - Environmental pollution
KW - Toxicity
UR - http://www.scopus.com/inward/record.url?scp=85112534508&partnerID=8YFLogxK
U2 - 10.1007/s11356-021-14700-0
DO - 10.1007/s11356-021-14700-0
M3 - Review article
C2 - 34196863
AN - SCOPUS:85112534508
SN - 0944-1344
VL - 28
SP - 44587
EP - 44597
JO - Environmental Science and Pollution Research
JF - Environmental Science and Pollution Research
IS - 33
ER -