Aluminum environmental pollution: the silent killer

Reema H. Alasfar, Rima J. Isaifan*

*Corresponding author for this work

    Research output: Contribution to journalReview articlepeer-review

    134 Citations (Scopus)

    Abstract

    The concern about aluminum (Al) toxicity has been proven in various cases. Some cases are associated with the fact that Al is a neurotoxic substance that has been found in high levels in the brain tissues of Alzheimer’s disease (AD), epilepsy, and autism patients. Other cases are related to infants, especially premature infants and ones with renal failure, who are at the risk of developing the central nervous system (CNS) and bone toxicity. This risk is a result of infants’ exposure to Al from milk formulas, intravenous-feeding solutions, and possibly from aluminum-containing vaccinations. Furthermore, most antiperspirants contain aluminum compounds that raise human exposure to toxic Al. This review paper is intended to discuss in detail the above concerns associated with aluminum, and hence urges the need for more studies exploring the effects of overexposure to Al and recommending mitigation actions.

    Original languageEnglish
    Pages (from-to)44587-44597
    Number of pages11
    JournalEnvironmental Science and Pollution Research
    Volume28
    Issue number33
    DOIs
    Publication statusPublished - Sept 2021

    Keywords

    • Aluminum
    • Alzheimer disease
    • Environmental pollution
    • Toxicity

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