Abstract
Neurodegenerative disorders are desperately lacking treatment options. It is imperative that drug repurposing be considered in the fight against neurodegenerative diseases. Fenamates have been studied for efficacy in treating several neurodegenerative diseases. The purpose of this review is to comprehensively present the past and current research on fenamates in the context of neurodegenerative diseases with a special emphasis on tolfenamic acid and Alzheimer’s disease. Furthermore, this review discusses the major molecular pathways modulated by fenamates.
| Original language | English |
|---|---|
| Article number | 702 |
| Pages (from-to) | 1-16 |
| Number of pages | 16 |
| Journal | Cells |
| Volume | 10 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - Mar 2021 |
| Externally published | Yes |
Keywords
- Alzheimer’s disease
- Fenamate
- Flufenamic acid
- Meclofenamic acid
- Mefenamic acid
- NSAID
- Neurodegenerative
- Tolfenamic acid