TY - JOUR
T1 - Genomic and proteomic characterization of embryonic stem cells
AU - Stanton, Lawrence W.
AU - Bakre, Manjiri M.
PY - 2007/8
Y1 - 2007/8
N2 - Stem cell biology, like all areas of cell biology, has been significantly affected by the arrival of the genomics era. The rendering of the human and mouse genome sequences and the development of attendant technologies have made it possible to comprehensively explore embryonic stem cell biology at the molecular level. Recently, there has been emphasis on global characterization of the transcriptome, epigenome, and proteome of embryonic stem cells. These omic evaluations of embryonic stem cells are leading to improved methods for cell-based therapies and are advancing our basic understanding of early embryonic development.
AB - Stem cell biology, like all areas of cell biology, has been significantly affected by the arrival of the genomics era. The rendering of the human and mouse genome sequences and the development of attendant technologies have made it possible to comprehensively explore embryonic stem cell biology at the molecular level. Recently, there has been emphasis on global characterization of the transcriptome, epigenome, and proteome of embryonic stem cells. These omic evaluations of embryonic stem cells are leading to improved methods for cell-based therapies and are advancing our basic understanding of early embryonic development.
UR - http://www.scopus.com/inward/record.url?scp=34548126501&partnerID=8YFLogxK
U2 - 10.1016/j.cbpa.2007.05.029
DO - 10.1016/j.cbpa.2007.05.029
M3 - Review article
C2 - 17646122
AN - SCOPUS:34548126501
SN - 1367-5931
VL - 11
SP - 399
EP - 404
JO - Current Opinion in Chemical Biology
JF - Current Opinion in Chemical Biology
IS - 4
ER -