In Vitro Models to Study the Regulatory Roles of Retinoids in Angiogenesis

Ayman Al Haj Zen*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

3 Citations (Scopus)

Abstract

Retinoids are reported to regulate vascular growth and remodeling during embryonic development and wound healing. A better understanding of angiogenic mechanisms of retinoids has clinical implication in pathological conditions such as chronic nonhealing wounds. Here, we describe in vitro angiogenesis assays that can be a useful tool to study the role of retinoids and retinoic acid signaling in the regulation of different features of angiogenesis such as tubulogenesis and branching.

Original languageEnglish
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages73-83
Number of pages11
DOIs
Publication statusPublished - 2019

Publication series

NameMethods in Molecular Biology
Volume2019
ISSN (Print)1064-3745
ISSN (Electronic)1940-6029

Keywords

  • Angiogenesis
  • Coculture
  • Endothelial cells
  • Retinoids
  • Tube formation
  • Wound healing

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