PopMLvis: a tool for analysis and visualization of population structure using genotype data from genome-wide association studies

Mohamed Elshrif*, Keivin Isufaj, Khalid Kunji, Mohamad Saad*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

One of the aims of population genetics is to identify genetic differences/similarities among individuals of multiple ancestries. Many approaches including principal component analysis, clustering, and maximum likelihood techniques can be used to assign individuals to a given ancestry based on their genetic makeup. Although there are several tools that implement such algorithms, there is a lack of interactive visual platforms to run a variety of algorithms in one place. Therefore, we developed PopMLvis, a platform that offers an interactive environment to visualize genetic similarity data using several algorithms, and generate figures that can be easily integrated into scientific articles.

Original languageEnglish
Article number298
JournalBMC Bioinformatics
Volume25
Issue number1
DOIs
Publication statusPublished - Dec 2024

Keywords

  • Bioinformatics software
  • GWAS analysis
  • Machine learning
  • Population genetics

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