TY - JOUR
T1 - Sensors-based monitoring and treatment approaches for in-stent restenosis
AU - Yi, Ying
AU - Wang, Bo
AU - Li, Changping
N1 - Publisher Copyright:
© 2022 Wiley Periodicals LLC.
PY - 2023/2
Y1 - 2023/2
N2 - Cardiovascular disease (CVD) can progressively narrow arteries due to plaque accumulation on the inner walls of the blood vessels, which results in an obstructed blood flow, leading to heart attack, stroke, and even death if the obstruction is severe. A popular treatment for the disease is to use an intravascular mechanical device called the stent to achieve an immediate restoration of blood flow. However, the physical stimulation induced by the stent expansion can cause inflammation of the vessel tissue. As one of the most common post-stenting complications, re-narrowing of the vessel is the main pathology that leads to in-stent restenosis (ISR), induced by the excess growth of the tissue over the deployed stent. The ISR is widely recognized as a significant cause of death globally if early symptoms are not detected. Hence, monitoring and early diagnosis indeed matter when it comes to treatment. The latest technologies for monitoring and treatments of ISR were reviewed in this work, and the potential issues and suggestions related to the reported technologies were presented. The target of this review aims to positively prompt researchers to develop an advanced stent system in terms of its electromechanical performance, size, functional feature, feasibility, and reliability.
AB - Cardiovascular disease (CVD) can progressively narrow arteries due to plaque accumulation on the inner walls of the blood vessels, which results in an obstructed blood flow, leading to heart attack, stroke, and even death if the obstruction is severe. A popular treatment for the disease is to use an intravascular mechanical device called the stent to achieve an immediate restoration of blood flow. However, the physical stimulation induced by the stent expansion can cause inflammation of the vessel tissue. As one of the most common post-stenting complications, re-narrowing of the vessel is the main pathology that leads to in-stent restenosis (ISR), induced by the excess growth of the tissue over the deployed stent. The ISR is widely recognized as a significant cause of death globally if early symptoms are not detected. Hence, monitoring and early diagnosis indeed matter when it comes to treatment. The latest technologies for monitoring and treatments of ISR were reviewed in this work, and the potential issues and suggestions related to the reported technologies were presented. The target of this review aims to positively prompt researchers to develop an advanced stent system in terms of its electromechanical performance, size, functional feature, feasibility, and reliability.
KW - Biomechanics
KW - Biosensors
KW - Cardiovascular
UR - http://www.scopus.com/inward/record.url?scp=85138653656&partnerID=8YFLogxK
U2 - 10.1002/jbm.b.35164
DO - 10.1002/jbm.b.35164
M3 - Review article
C2 - 36161478
AN - SCOPUS:85138653656
SN - 1552-4973
VL - 111
SP - 490
EP - 498
JO - Journal of Biomedical Materials Research - Part B Applied Biomaterials
JF - Journal of Biomedical Materials Research - Part B Applied Biomaterials
IS - 2
ER -