TY - JOUR
T1 - Sunni Islamic perspectives on lab-grown sperm and eggs derived from stem cells–in vitro gametogenesis (IVG)
AU - Serour, Gamal
AU - Ghaly, Mohammed
AU - Saifuddeen, Shaikh Mohd
AU - Anwar, Ayaz
AU - Isa, Noor Munirah
AU - Chin, Alexis Heng Boon
N1 - Publisher Copyright:
© 2022 Informa UK Limited, trading as Taylor & Francis Group.
PY - 2023
Y1 - 2023
N2 - An exciting development in the field of assisted reproductive technologies is In Vitro Gametogenesis (IVG) that enables production of functional gametes from stem cells in the laboratory. Currently, development of this technology is still at an early stage and has demonstrated to work only in rodents. Upon critically examining the ethical dimensions of various possible IVG applications in human fertility treatment from a Sunni Islamic perspective, together with benefit-harm (maslahah-mafsadah) assessment; it is concluded that utilization of IVG, once its efficacy and safety are guaranteed, could be permissible by strictly adhering to Islamic ethical principles related to marriage, biological/genetic relatedness, sexual intercourse, and moral status of the embryo/fetus versus that of the gamete. As a result, IVG will be acceptable for treating primary infertility, age-related infertility, and preventing genetic diseases. However, it will be unacceptable for application in posthumous reproduction, donor gametes, genetic enhancement, and procreation in same-sex couples.
AB - An exciting development in the field of assisted reproductive technologies is In Vitro Gametogenesis (IVG) that enables production of functional gametes from stem cells in the laboratory. Currently, development of this technology is still at an early stage and has demonstrated to work only in rodents. Upon critically examining the ethical dimensions of various possible IVG applications in human fertility treatment from a Sunni Islamic perspective, together with benefit-harm (maslahah-mafsadah) assessment; it is concluded that utilization of IVG, once its efficacy and safety are guaranteed, could be permissible by strictly adhering to Islamic ethical principles related to marriage, biological/genetic relatedness, sexual intercourse, and moral status of the embryo/fetus versus that of the gamete. As a result, IVG will be acceptable for treating primary infertility, age-related infertility, and preventing genetic diseases. However, it will be unacceptable for application in posthumous reproduction, donor gametes, genetic enhancement, and procreation in same-sex couples.
KW - Ethics
KW - Fatwa
KW - Islam
KW - Muslims
KW - oocytes
KW - spermatozoa
UR - http://www.scopus.com/inward/record.url?scp=85142696946&partnerID=8YFLogxK
U2 - 10.1080/20502877.2022.2142094
DO - 10.1080/20502877.2022.2142094
M3 - Article
C2 - 36427532
AN - SCOPUS:85142696946
SN - 2050-2877
VL - 29
SP - 108
EP - 120
JO - New Bioethics
JF - New Bioethics
IS - 2
ER -