Synthesis, spectral and in vitro biological studies of bis- triorganogermyl(substituted)propionates of triarylantimony(V) X-ray studies of triphenylgermyl-n-propyl propionic acid

Muhammad Kaleem Khosa; Muhammad Mazhar; Saqib Ali; Sarim Dastgir; Masood Parvez; Farkhanda Shaheen; Abdul Malik; Shahid Mahboob Rana

doi:10.1080/15533170600862903

Synthesis, spectral and in vitro biological studies of bis- triorganogermyl(substituted)propionates of triarylantimony(V) X-ray studies of triphenylgermyl-n-propyl propionic acid

Muhammad Kaleem Khosa^*, Muhammad Mazhar, Saqib Ali, Sarim Dastgir, Masood Parvez, Farkhanda Shaheen, Abdul Malik, Shahid Mahboob Rana

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

New compounds of Bis-triorganogermyl(substituted) propionates of triarylantimony(V) with general formula (¹R₃-GeCHR ²CH₂CO₂)₂SbAr₃ have been synthesized and characterized by various techniques such as elemental analyses; FT-IR, ¹HNMR, ¹³CNMR and mass spectrometry. All these compounds have distorted trigonal bipyramidal geometry around antimony in both solid states as well as in non-coordinated solvents. The single X-ray analysis of precursor triphenylgermyl-n-propyl propionic acid (Ph₃GeCH-(n- C₃H₇)CH₂COOH) have revealed dimeric structure of molecule through strong hydrogen bonding in conventional manner in which germanium has slightly distorted tetrahedral geometry. Selected numbers of compounds screened against different strains of bacteria and fungus show good activity.

Original language	English
Pages (from-to)	575-584
Number of pages	10
Journal	Synthesis and Reactivity in Inorganic, Metal-Organic and Nano-Metal Chemistry
Volume	36
Issue number	7
DOIs	https://doi.org/10.1080/15533170600862903
Publication status	Published - 1 Aug 2006
Externally published	Yes

Keywords

Antimony carboxylates
Biological studies
Germanium
X-ray studies

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10.1080/15533170600862903

Cite this

Khosa, M. K., Mazhar, M., Ali, S., Dastgir, S., Parvez, M., Shaheen, F., Malik, A., & Rana, S. M. (2006). Synthesis, spectral and in vitro biological studies of bis- triorganogermyl(substituted)propionates of triarylantimony(V) X-ray studies of triphenylgermyl-n-propyl propionic acid. Synthesis and Reactivity in Inorganic, Metal-Organic and Nano-Metal Chemistry, 36(7), 575-584. https://doi.org/10.1080/15533170600862903

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title = "Synthesis, spectral and in vitro biological studies of bis- triorganogermyl(substituted)propionates of triarylantimony(V) X-ray studies of triphenylgermyl-n-propyl propionic acid",

abstract = "New compounds of Bis-triorganogermyl(substituted) propionates of triarylantimony(V) with general formula (1R3-GeCHR 2CH2CO2)2SbAr3 have been synthesized and characterized by various techniques such as elemental analyses; FT-IR, 1HNMR, 13CNMR and mass spectrometry. All these compounds have distorted trigonal bipyramidal geometry around antimony in both solid states as well as in non-coordinated solvents. The single X-ray analysis of precursor triphenylgermyl-n-propyl propionic acid (Ph3GeCH-(n- C3H7)CH2COOH) have revealed dimeric structure of molecule through strong hydrogen bonding in conventional manner in which germanium has slightly distorted tetrahedral geometry. Selected numbers of compounds screened against different strains of bacteria and fungus show good activity.",

keywords = "Antimony carboxylates, Biological studies, Germanium, X-ray studies",

author = "Khosa, {Muhammad Kaleem} and Muhammad Mazhar and Saqib Ali and Sarim Dastgir and Masood Parvez and Farkhanda Shaheen and Abdul Malik and Rana, {Shahid Mahboob}",

year = "2006",

month = aug,

day = "1",

doi = "10.1080/15533170600862903",

language = "English",

volume = "36",

pages = "575--584",

journal = "Synthesis and Reactivity in Inorganic, Metal-Organic and Nano-Metal Chemistry",

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Khosa, MK, Mazhar, M, Ali, S, Dastgir, S, Parvez, M, Shaheen, F, Malik, A & Rana, SM 2006, 'Synthesis, spectral and in vitro biological studies of bis- triorganogermyl(substituted)propionates of triarylantimony(V) X-ray studies of triphenylgermyl-n-propyl propionic acid', Synthesis and Reactivity in Inorganic, Metal-Organic and Nano-Metal Chemistry, vol. 36, no. 7, pp. 575-584. https://doi.org/10.1080/15533170600862903

Synthesis, spectral and in vitro biological studies of bis- triorganogermyl(substituted)propionates of triarylantimony(V) X-ray studies of triphenylgermyl-n-propyl propionic acid. / Khosa, Muhammad Kaleem; Mazhar, Muhammad; Ali, Saqib et al.
In: Synthesis and Reactivity in Inorganic, Metal-Organic and Nano-Metal Chemistry, Vol. 36, No. 7, 01.08.2006, p. 575-584.

Research output: Contribution to journal › Article › peer-review

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T1 - Synthesis, spectral and in vitro biological studies of bis- triorganogermyl(substituted)propionates of triarylantimony(V) X-ray studies of triphenylgermyl-n-propyl propionic acid

AU - Khosa, Muhammad Kaleem

AU - Mazhar, Muhammad

AU - Ali, Saqib

AU - Dastgir, Sarim

AU - Parvez, Masood

AU - Shaheen, Farkhanda

AU - Malik, Abdul

AU - Rana, Shahid Mahboob

PY - 2006/8/1

Y1 - 2006/8/1

N2 - New compounds of Bis-triorganogermyl(substituted) propionates of triarylantimony(V) with general formula (1R3-GeCHR 2CH2CO2)2SbAr3 have been synthesized and characterized by various techniques such as elemental analyses; FT-IR, 1HNMR, 13CNMR and mass spectrometry. All these compounds have distorted trigonal bipyramidal geometry around antimony in both solid states as well as in non-coordinated solvents. The single X-ray analysis of precursor triphenylgermyl-n-propyl propionic acid (Ph3GeCH-(n- C3H7)CH2COOH) have revealed dimeric structure of molecule through strong hydrogen bonding in conventional manner in which germanium has slightly distorted tetrahedral geometry. Selected numbers of compounds screened against different strains of bacteria and fungus show good activity.

AB - New compounds of Bis-triorganogermyl(substituted) propionates of triarylantimony(V) with general formula (1R3-GeCHR 2CH2CO2)2SbAr3 have been synthesized and characterized by various techniques such as elemental analyses; FT-IR, 1HNMR, 13CNMR and mass spectrometry. All these compounds have distorted trigonal bipyramidal geometry around antimony in both solid states as well as in non-coordinated solvents. The single X-ray analysis of precursor triphenylgermyl-n-propyl propionic acid (Ph3GeCH-(n- C3H7)CH2COOH) have revealed dimeric structure of molecule through strong hydrogen bonding in conventional manner in which germanium has slightly distorted tetrahedral geometry. Selected numbers of compounds screened against different strains of bacteria and fungus show good activity.

KW - Antimony carboxylates

KW - Biological studies

KW - Germanium

KW - X-ray studies

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DO - 10.1080/15533170600862903

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JO - Synthesis and Reactivity in Inorganic, Metal-Organic and Nano-Metal Chemistry

JF - Synthesis and Reactivity in Inorganic, Metal-Organic and Nano-Metal Chemistry

IS - 7

ER -

Khosa MK, Mazhar M, Ali S, Dastgir S, Parvez M, Shaheen F et al. Synthesis, spectral and in vitro biological studies of bis- triorganogermyl(substituted)propionates of triarylantimony(V) X-ray studies of triphenylgermyl-n-propyl propionic acid. Synthesis and Reactivity in Inorganic, Metal-Organic and Nano-Metal Chemistry. 2006 Aug 1;36(7):575-584. doi: 10.1080/15533170600862903

Synthesis, spectral and in vitro biological studies of bis- triorganogermyl(substituted)propionates of triarylantimony(V) X-ray studies of triphenylgermyl-n-propyl propionic acid

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