The Muscle-Bound Heart

Marwan M. Refaat; Akl C. Fahed; Sylvana Hassanieh; Mostafa Hotait; Mariam Arabi; Hadi Skouri; Jonathan G. Seidman; Christine E. Seidman; Fadi F. Bitar; Georges Nemer

doi:10.1016/j.ccep.2015.10.034

The Muscle-Bound Heart

Marwan M. Refaat^*, Akl C. Fahed, Sylvana Hassanieh, Mostafa Hotait, Mariam Arabi, Hadi Skouri, Jonathan G. Seidman, Christine E. Seidman, Fadi F. Bitar, Georges Nemer

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

6 Citations (Scopus)

Abstract

Hypertrophic cardiomyopathy (HCM) is a familial cardiac disease manifested in a wide phenotype and diverse genotype and, thus, presenting unpredictable risks mainly on young adults. Extensive studies are being conducted to categorize patients and link phenotype with genotype for a better management and control of the disease with all its complications. Because the full mechanisms behind HCM are still not revealed, therapeutics are not definitive. Further research is to be conducted for the generation of a complete picture and directed therapy for HCM.

Original language	English
Pages (from-to)	223-231
Number of pages	9
Journal	Cardiac Electrophysiology Clinics
Volume	8
Issue number	1
DOIs	https://doi.org/10.1016/j.ccep.2015.10.034
Publication status	Published - 1 Mar 2016
Externally published	Yes

Keywords

Genotype
Hypertrophic cardiomyopathy
Left ventricle
Muscle-bound heart
Phenotype

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10.1016/j.ccep.2015.10.034

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title = "The Muscle-Bound Heart",

abstract = "Hypertrophic cardiomyopathy (HCM) is a familial cardiac disease manifested in a wide phenotype and diverse genotype and, thus, presenting unpredictable risks mainly on young adults. Extensive studies are being conducted to categorize patients and link phenotype with genotype for a better management and control of the disease with all its complications. Because the full mechanisms behind HCM are still not revealed, therapeutics are not definitive. Further research is to be conducted for the generation of a complete picture and directed therapy for HCM.",

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AU - Refaat, Marwan M.

AU - Fahed, Akl C.

AU - Hassanieh, Sylvana

AU - Hotait, Mostafa

AU - Arabi, Mariam

AU - Skouri, Hadi

AU - Seidman, Jonathan G.

AU - Seidman, Christine E.

AU - Bitar, Fadi F.

AU - Nemer, Georges

PY - 2016/3/1

Y1 - 2016/3/1

N2 - Hypertrophic cardiomyopathy (HCM) is a familial cardiac disease manifested in a wide phenotype and diverse genotype and, thus, presenting unpredictable risks mainly on young adults. Extensive studies are being conducted to categorize patients and link phenotype with genotype for a better management and control of the disease with all its complications. Because the full mechanisms behind HCM are still not revealed, therapeutics are not definitive. Further research is to be conducted for the generation of a complete picture and directed therapy for HCM.

AB - Hypertrophic cardiomyopathy (HCM) is a familial cardiac disease manifested in a wide phenotype and diverse genotype and, thus, presenting unpredictable risks mainly on young adults. Extensive studies are being conducted to categorize patients and link phenotype with genotype for a better management and control of the disease with all its complications. Because the full mechanisms behind HCM are still not revealed, therapeutics are not definitive. Further research is to be conducted for the generation of a complete picture and directed therapy for HCM.

KW - Genotype

KW - Hypertrophic cardiomyopathy

KW - Left ventricle

KW - Muscle-bound heart

KW - Phenotype

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JO - Cardiac Electrophysiology Clinics

JF - Cardiac Electrophysiology Clinics

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The Muscle-Bound Heart

Abstract

Keywords

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