The ribosome's comeback: new role in body weight regulation

Luma Srour; Nady El Hajj

doi:10.1016/j.tig.2024.07.006

The ribosome's comeback: new role in body weight regulation

Luma Srour, Nady El Hajj^*

^*Corresponding author for this work

Genomics and Translational Biomedicine

Hamad bin Khalifa University

Research output: Contribution to journal › Editorial

Abstract

The recent discovery of an association between ribosomal DNA (rDNA) copy number and body mass index (BMI) by Law et al. sheds light on a possible role of 45S rDNA in body-weight regulation. This finding opens new avenues for further investigations into the effect of rDNA on various human phenotypes.

Original language	English
Pages (from-to)	815-816
Number of pages	2
Journal	Trends in Genetics
Volume	40
Issue number	10
DOIs	https://doi.org/10.1016/j.tig.2024.07.006
Publication status	Published - Oct 2024

Keywords

DNA methylation
body mass
rDNA copy number
ribosomal DNA

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10.1016/j.tig.2024.07.006

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title = "The ribosome's comeback: new role in body weight regulation",

abstract = "The recent discovery of an association between ribosomal DNA (rDNA) copy number and body mass index (BMI) by Law et al. sheds light on a possible role of 45S rDNA in body-weight regulation. This finding opens new avenues for further investigations into the effect of rDNA on various human phenotypes.",

keywords = "DNA methylation, body mass, rDNA copy number, ribosomal DNA",

author = "Luma Srour and {El Hajj}, Nady",

note = "Publisher Copyright: {\textcopyright} 2024 Elsevier Ltd",

year = "2024",

month = oct,

doi = "10.1016/j.tig.2024.07.006",

language = "English",

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AU - Srour, Luma

AU - El Hajj, Nady

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N2 - The recent discovery of an association between ribosomal DNA (rDNA) copy number and body mass index (BMI) by Law et al. sheds light on a possible role of 45S rDNA in body-weight regulation. This finding opens new avenues for further investigations into the effect of rDNA on various human phenotypes.

AB - The recent discovery of an association between ribosomal DNA (rDNA) copy number and body mass index (BMI) by Law et al. sheds light on a possible role of 45S rDNA in body-weight regulation. This finding opens new avenues for further investigations into the effect of rDNA on various human phenotypes.

KW - DNA methylation

KW - body mass

KW - rDNA copy number

KW - ribosomal DNA

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U2 - 10.1016/j.tig.2024.07.006

DO - 10.1016/j.tig.2024.07.006

M3 - Editorial

AN - SCOPUS:85200051145

SN - 0168-9525

VL - 40

SP - 815

EP - 816

JO - Trends in Genetics

JF - Trends in Genetics

IS - 10

ER -

The ribosome's comeback: new role in body weight regulation

Abstract

Keywords

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