TY - GEN
T1 - Virtual environment for processing medial axis representations of 3D nanoscale reconstructions of brain cellular structures
AU - Boges, Daniya
AU - Calí, Corrado
AU - Magistretti, Pierre
AU - Hadwiger, Markus
AU - Sicat, Ronell
AU - Agus, Marco
N1 - Publisher Copyright:
© 2019 Copyright held by the owner/author(s).
PY - 2019/11/12
Y1 - 2019/11/12
N2 - We present a novel immersive environment for the interactive analysis of nanoscale cellular reconstructions of rodent brain samples acquired through electron microscopy. The system is focused on medial axis representations (skeletons) of branched and tubular structures of brain cells, and it is specifically designed for: i) effective semi-automatic creation of skeletons from surface-based representations of cells and structures ii) fast proofreading, i.e., correcting and editing of semi-automatically constructed skeleton representations, and iii) useful exploration, i.e., measuring, comparing, and analyzing geometric features related to cellular structures based on medial axis representations. The application runs in a standard PC-tethered virtual reality (VR) setup with a head mounted display (HMD), controllers, and tracking sensors. The system is currently used by neuroscientists for performing morphology studies on sparse reconstructions of glial cells and neurons extracted from a sample of the somatosensory cortex of a juvenile rat.
AB - We present a novel immersive environment for the interactive analysis of nanoscale cellular reconstructions of rodent brain samples acquired through electron microscopy. The system is focused on medial axis representations (skeletons) of branched and tubular structures of brain cells, and it is specifically designed for: i) effective semi-automatic creation of skeletons from surface-based representations of cells and structures ii) fast proofreading, i.e., correcting and editing of semi-automatically constructed skeleton representations, and iii) useful exploration, i.e., measuring, comparing, and analyzing geometric features related to cellular structures based on medial axis representations. The application runs in a standard PC-tethered virtual reality (VR) setup with a head mounted display (HMD), controllers, and tracking sensors. The system is currently used by neuroscientists for performing morphology studies on sparse reconstructions of glial cells and neurons extracted from a sample of the somatosensory cortex of a juvenile rat.
KW - Immersive neuroscience
KW - Nanoscale brain reconstruction
UR - http://www.scopus.com/inward/record.url?scp=85076153947&partnerID=8YFLogxK
U2 - 10.1145/3359996.3365042
DO - 10.1145/3359996.3365042
M3 - Conference contribution
AN - SCOPUS:85076153947
T3 - Proceedings of the ACM Symposium on Virtual Reality Software and Technology, VRST
BT - Proceedings - VRST 2019
A2 - Spencer, Stephen N.
PB - Association for Computing Machinery
T2 - 25th ACM Symposium on Virtual Reality Software and Technology, VRST 2019
Y2 - 12 November 2019 through 15 November 2019
ER -